In the Bible, concerning the end time, we read:
Daniel 12:1-3 And at that time shall Michael stand up, the great prince which standeth for the children of thy people: and there shall be a time of trouble, such as never was since there was a nation even to that same time: and at that time thy people shall be delivered, every one that shall be found written in the book. 2 And many of them that sleep in the dust of the earth shall awake, some to everlasting life, and some to shame and everlasting contempt. 3 And they that be wise shall shine as the brightness of the firmament; and they that turn many to righteousness as the stars for ever and ever.
During the plagues, the scientists will look for reasons for the various happenings, as they always look for reasons.
But in Daniel 12:10, we read: Many shall be purified, and made white, and tried; but the wicked shall do wickedly: and none of the wicked shall understand; but the wise shall understand.
The plagues and woes of the great tribulation are divided into two parts.
The first seven plagues are loosed by individual angels who sound their trumpets.
Revelation 8 & 9
The first trumpet sounds and there comes hail and fire mingled with blood coming on 1/3 of the earth.
The second trumpet sounds and a great mountain burning with fire is cast into the sea and 1/3 of the sea became blood and the 1/3 part of the creatures in the sea died and 1/3 part of the ships were destroyed.
The third trumpet sounds and a great star which was burning fell from heaven and it fell upon 1/3 part of the rivers and the fountains of waters and the waters became bitter and many men died of the waters.
The fourth trumpet sounds and the third part of the sun and moon and stars were "smitten" so they were dark, and the day shown not for 1/3 part and the night likewise.
The fifth trumpet sounded and a great star fell from heaven and to him was given the key of the bottomless pit which he unlocked, bringing smoke of a great furnace which darkened the sun and air and out of the smoke came locust upon the earth and they had great power to hurt those men for five months who did not have the seal of God in their foreheads.
The sixth trumpet sounded and the 4 angels which were bound in the Euphrates were loosed and killed the third part of men.
The seventh angel sounded and made the declaration that there should be time no more.
Then 7 more angels poured out vials of the wrath of God upon the earth:
Revelation 16 (each angel pored out a vial of the wrath of God)
* There fell a smelly and grievous sore upon the men which had the mark of the beast and which worshipped the image of the beast.
* The sea became as the blood of a dead man and every living soul died in the sea.
* The fountains and rivers of water became blood.
* The vial was poured out on the sun and great heat scorched men with fire.
* The next vial was poured out on the seat of "the beast" and his kingdom was made full of darkness and the men of his kingdom suffered pain and gnawed their tongues.
* The sixth vial was poured on the river Euphrates and the water dried up, and three unclean spirits like frogs came out of the mouth of the dragon and the beast and the false prophet, for they are the spirits of devils working miracles.
* The seventh angel poured out his vial into the air and a great voice from heaven said, "It is done." And there were voices, and thunders, and lightnings and a great earthquake, and the cities of nations fell, and every island fled away and every mountain disappeared, and great hail fell, and men blasphemed God.
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